A school bus with 40 students onboard crashed into a semi in Bradenton on Thursday, leaving 21 injured. According to officials, the school bus crashed into the back of the semi at State Road 64 East and 66th Street Court East in Bradenton. Manatee County School District spokesperson Margi Nanney and FHP officials said 21 people were hurt and taken to local hospitals. The most seriously injured student was believed to have broken her femur.