Several cars of an Amtrak train traveling from Los Angeles to Chicago derailed Monday afternoon after it struck a dump truck at a crossing in northern Missouri, Amtrak announced.

More than 200 people were on board the train at the time of the crash, which was first reported about 12:43 p.m. near Mendon, Missouri, according to the Missouri State Highway Patrol.

Three people were killed in the crash, the patrol said, including two people on the train and one person in the dump truck.

A spokesman for the patrol said the total number injured was not known, but Missouri hospitals counted at least 51 patients by 7 p.m.